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Chelation Therapy

What is Chelation Therapy

Chelation therapy is a safe, effective alternative to the drugs and surgery used to treat many illnesses caused or made worse by athero/arteriosclerosis. While drugs and surgery address the symptoms of a disease, chelation therapy goes directly to its causes and reverses the damaging process. Chelation therapy involves the intravenous infusion of ethylene diamine tetra-acetic acid (EDTA). EDTA removes toxic heavy metals (such as lead) and abnormally located/excessive metallic ions (such as iron) from the body thereby cleansing blood, vessels and organs and improving metabolic and circulatory function.

Comparison

Bypass surgery is the mechanical repair of only a small portion of the arterial tree. Total costs vary from $30,000 to $50,000 or more. Chelation therapy improves the flow of blood through the entire vascular system. Total costs vary from $2,000 to $4,000 for 20 to 40 treatments.

Prevention of Arterio/Atherosclerosis

As in the prevention of most diseases, diet and exercise also play very important roles in the prevention of arterio/atherosclerosis.

Specifically what are some things we can do?

a)      Reduce exposure to herbicides, pesticides and preservatives in our food by buying organic or planting your own garden

b)      Cut down on cholesterol by shifting to a vegetarian, low fat, high carbohydrate diet.

c)      Increase intake of antioxidants such as beta carotene (precursor to Vitamin A) and Vitamin C, which bind to and eliminate free radicals.

d)     Ingest oral chelating agents such as Vitamin C from citrus fruits. Fresh vegetables are packed with natural and effecting chelating agents!

e)      Exercise increases your body’s ability to reduce free radicals. In addition, lactic acid (the metabolic waste product produced by sustained vigorous muscle contraction) is an excellent chelating agent.

How long does chelation therapy take?

Length of treatment varies with each patient. Each treatment lasts from 2-4 hours. The EDTA solution is infused as a very slow drip into a vein in the arm. Typically 20-30 treatments administered weekly or biweekly are the recommended course. Surprisingly, young adults have benefited from using this therapy preventatively once every 3 months.

Are there any risks or unpleasant side effects?

When administered and monitored properly, side effects are very rare and minimal: mild nausea, dizziness or headache. Frequency of treatment and dosages are tailored to individual kidney function and the patient’s ability to safely excrete EDTA in the urine. Kidney functions are monitored throughout the course of the therapy to ensure against overload. Since the half-life of EDTA in the body is only one hour, within 24 hours all the EDTA is gone from the body and you are left only with its therapeutic effect.

Interactions with other treatments

Chelation therapy can be used in conjunction with most other therapies for cardio-vascular disease such as blood thinners, calcium blockers, beta blockers, blood vessel dilators as well as medicines for blood pressures and heart arrhythmias. A course of chelation typically reduces/eliminates the need for drugs.

Atherosclerosis and chelation

Atherosclerosis (hardening of the arteries) is a result of many factors, including abnormal accumulations of metallic elements. The abnormal accumulations result in the formation of plaques within arteries. Plaques are composed of cholesterol, calcium and fibrous tissue. They block the flow of blood within the arteries, thereby starving vital organs of oxygen and other nutrients. When starved of oxygen, nutrients cell walls become leaky and dysfunctional allowing entry to excessive amounts of several elements including calcium, and sodium. When calcium accumulates to a critical point, deposits form like concrete. These calcifications can often be seen on x-ray. Disordered calcium metabolism can also cause coronaries and other arteries to go into spasm, further reducing blood to vital organs.

Is chelation for me?

Some signs that suggest that coronary arteries are not delivering enough blood to some area of the heart are:

-chest/leg pain on walking

-shortness of breath

-painful, discolored feet

-transient loss of vision

-paralysis

-memory loss

Sufferers of cardiovascular disease, strokes, Alzheimer’s, diabetes and those experiencing adverse reactions to pollutants are only a few of those who can benefit from chelation.

The vascular lab at our clinic allows noninvasive diagnosis of vascular functions. Unexplained symptoms which affect your heart, head or limbs can be explored for blockage to determine the presence and extent of coronary arterial disease. The lab also allows patient progress to be monitored by follow up tests.

Specific roles of EDTA

EDTA completely blocks harmful free radical chain reactions serving as a powerful antioxidant by binding and removing the metals that would otherwise catalyze those reactions.

What is free radical pathology?

Free radical pathology is the common denominator of an important contributing cause of atherosclerosis, cancer, diabetes and other degenerative diseases. Since free radical production is catalyzed by heavy metals, the continuing increase of automotive emissions as well as dust from automobile exhausts that contain lead, cadmium and other carcinogens, have led to increased free radical propagated disease.

How does chelation therapy restrict free radical proliferation?

Unbound metallic catalysts must be present for uncontrolled free radical proliferation to take place in a living tissue. Chelation therapy through the action of EDTA exhibits a strong attraction for these loosely bound metals allowing for their removal from the body. This permit the body’s antioxidant defenses to regain control.

EDTA removes toxic metals (such as lead, cadmium, aluminum) that interfere with normal metabolism and allow build up to accumulate on blood vessel walls. In addition EDTA removes abnormally located metals ions (such as copper and iron) which accumulate with age. Removing these metals restores enzyme systems to their proper functions.

EDTA mobilizes the calcium in soft tissues where it should not be stored and moves it to the bones where it should be stored. It does this by stimulating the production of parathyroid hormone by the parathyroid glands. This hormone is the hormone responsible for the relocation of calcium.

EDTA increases tissue flexibility by uncoupling age related cross linkages which are responsible for loss of skin tone and wrinkling.

What is EDTA and how does it affect health?

EDTA’s mode of action

EDTA is a synthetic amino acid which has the characteristic of bonding to toxic/abnormally situated metals in the human body. In chelation therapy, EDTA is infused into the bloodstream where it then travels through the blood vessels and removes undesirable metals from the body by binding tightly to them thereby making them chemically inert and excretable through the urine.

Which metals are considered undesirable and why?

Heavy metals (such as lead, mercury, aluminum and cadmium) in addition to excessive/abnormally situated nutritional elements (such as iron) are toxic.

LEAD– Among other damaging effects, it inactivates the vital enzymes upon which so much depends. Unfortunately our environment brings us into frequent contact with it, especially in vehicle exhaust.

MERCURY– It is even more toxic than lead, causing damage to the immune system. We absorb mercury from the fillings in our teeth. Another source of mercury is excessive fish consumption. This poisonous metal builds up in the marine food chain.

ALUMINUM– It has been found in toxic concentrations in the brains of people with Alzheimer’s disease. Aluminum is in the food cooked in aluminum pots, in deodorants, in tap water, in baking powder, and some drugs and foods.

In our body these metals are undesirable as they are closely involved in promoting many diseases by catalyzing free radical pathology and inhibiting vital enzyme function.

 

DMPS Chelation

DMPS (Sodium 2, 3-dimercaptopropane-1-sulfonate) is a sulfonic acid salt with free SH-groups that forms complexes with heavy metals such as mercury, cadmium, arsenic, lead, copper, silver, tin, and others. This agent was first developed in China, was then introduced in Russia (used for workers injured by exposure to heavy metals), and went from there to West Germany. Professor Max Daunderer, M.D., in Munich published a number of papers on the use of DMPS. He found that DMPS is the ideal agent to detox patients that have suffered from amalgam toxicity after the fillings have been removed. Intravenous DMPS leads to dumping of large amounts of heavy metals through the kidneys. 50% are excreted during the six hours following the shot, 90% after 24 hours. Oral DMPS leads to excretion of heavy metals mostly via the stool, but has been in our experience much less effective. DMPS has been proven to be the ideal agent to “clean” the kidneys of heavy metal residues and improve kidney function in patients that have been exposed to heavy metals. Intravenous DMPS should not be used in patients that still have silver amalgam fillings. DMPS seems to appear in the saliva and dissolves the surfaces of the existing amalgam fillings. This process occurs over a series of several days. However, the blood concentration of DMPS lessens very quickly.

The mercury that comes out after the first DMPS shot usually represents only recent exposure, further injections will eventually get the slow body pools. The cells start “joyfully” dumping the heavy metal content into the connective tissue. However, if DMPS is not given again within a reasonable period of time, the heavy metals are redistributed again back from extracellular to intracellular.

The most consistent observation that we have made is that each patient treated several times with DMPS seems to become biologically younger (hair grows back, skin looks more supple and rosy, lab parameters shift back to normal). Chronic pain and neurological disease appear to be the most gratifying indications. Even though DMPS does not cross the blood brain barrier, major improvements in neurological disease are often seen. This is easily explained through the laws of osmosis: If the connective tissue and vascular system is free of heavy metals and the brain and the nervous system has a high heavy metal burden, given enough time, the heavy metals will shift from the brain into the other tissues where the body can excrete them.

 

DMSA Chelation

Meso-2, 3-dimercaptosuccinic acid (DMSA), is a water-soluble, sulfhydryl-containing compound which is an effective oral chelator of heavy metals. Initial studies over forty years ago identified DMSA as an effective antidote to heavy metal poisoning. DMSA was subsequently studied for twenty years in the People’s Republic of China, Japan, and Russia before scientists in Europe and the United States “discovered” the substance and its potential usefulness in the mid-1970s. DMSA is a dithiol (containing two sulfhydryl, or S-H, groups) and an analogue of dimercaprol (BAL, British Anti-Lewisite), a lipid-soluble compound also used for metal chelation. DMSA’s water solubility and oral dosing create a distinct advantage over BAL, which has a small therapeutic index and must be administered in an oil solution via painful, deep intramuscular injection. DMSA, on the other hand, has a large therapeutic window and is the least toxic of the dithiol compounds.

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